1、 Composition:

The reactor includes a touch screen chip control system, a set of bioreactors, a culture medium input and waste liquid output system, a culture medium flow acceleration rate control system, a liquid level control system, an air path system, and a temperature control system,PHControl system, mechanical lifting system, rack, shell, water tray, etc. We have developed a fully automated in vitro intestinal model that is easy to operate, convenient to use, and has good system stability,

2、 Application:

1Can be used for the study of gut microbiota, interactions between gut and microbiota, interactions between normal microbiota and pathogens, and interactions between antibiotics and normal microbiota

2Can be used for the development of new drugs, probiotics, and functional foods.

3The in vitro enrichment of uncultured intestinal bacteria will be beneficial for better understanding the function of intestinal microbiota and laying a solid foundation for the development of new products.

4、The four sets of continuous cultivation systems can be used separately for simulating gut microbiota cultivation, or they can be assembled into two-phase, three-phase, or even four phase continuous fermentation systems through elevators.

IIItechnologyAdvantages:

1Established models simulating the human and animal intestines;

2AdoptingPCR-DGGE、454The evaluation of sequencing and short chain fatty acid concentration measurement shows that the reactor has a good effect on simulating the microbiota of human feces and animal intestinal contents

3The reactor has good stability, repeatability, and wide applicability.

4It is possible to increase the proportion of uncultured bacteria in the fermentation broth and selectively enrich certain uncultured bacteria, which will help us better understand the functions of gut microbiota and the development of new products.